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What is the Endocannabinoid System (ECS)?

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With cannabis legalisation becoming more widespread around the world, more people are learning about cannabis. On the path to learning about cannabis, everyone will eventually come across the term ECS. ECS is the abbreviation for the endocannabinoid system. The endocannabinoid system is an essential part of every mammal on the planet. This unique part of our body helps control critical functions. The discovery of the endocannabinoid system came to light thanks to cannabinoid research. Even though current regulations around the world place barricades on cannabinoid research, researchers have still managed to conduct them.

Some of the earliest cannabinoid research began in the beginning of the 1900s. This research on cannabinoids ultimately helped lead to the discovery of the endocannabinoid system. Today science knows quite a bit about the ECS. Hui Chen Lu and Ken Mackie have described the ECS in a review published in 2015 in Biological Psychiatry. They describe it by saying, "The endocannabinoid system (ECS) is a widespread neuromodulatory system that plays important roles in central nervous system (CNS) development, synaptic plasticity, and the response to endogenous and environmental insults." Using CBD disposables as anxiety pen is also widely available as it contains no nicotine and just CBD.  Let's delve deep into understanding the difference between nicotine and CBD.

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Who Discovered the ECS?

The discovery of the ECS came from work started on cannabinoids by R.S. Cahn, Lord Todd, and Roger Adams in the early 1900s. Fast forward a few decades, and that research led to Raphael Mechoulam's discovery of THC. This research would lead way to the discovery of the endocannabinoid system and to what we know about the ECS today.

Since the discovery of the ECS occurred, it has been a focal point for researchers and drug developers. A deeper understanding of how this critical system works can unlock doors to all sorts of potential treatments. The research conducted on the ECS has been limited thanks to barriers blocking cannabinoid research; please note that when we mention cannabinoid we mean no THC as THC is a component that will make you high. Please note that THC vape juice is illegal in the UK.

However, it still has taken place enough that we understand what the ECS is and what it does. Let's look closely at what research is saying about the endocannabinoid system.

What Does Research Say About the ECS?

The ECS isn't something new, yet we still don't fully understand this vital part of human physiology. Research does show us that this is a critical part of every mammal on the planet. A literature review on the ECS published in 2007 states, "The endocannabinoid system regulates not only the central and peripheral mechanisms of food intake but also lipids synthesis and turnover in the liver and adipose tissue as well as glucose metabolism in muscle cells." Medical News Today says, "The endocannabinoid system (ECS) is a biological system in the body that helps regulate and balance key bodily functions."

We know that a healthy ECS is good but what happens when the ECS has a deficiency? An ECS deficiency can lead to all kinds of problems. Meliora Integrative Medicine says, "Like other systems in the body, the ECS can be thrown out of balance due to trauma, stress, or toxins. Clinical endocannabinoid deficiency can be associated with various conditions such as migraines, fibromyalgia, irritable bowel syndrome, inflammatory and neurologic conditions." There are a number of other benefits of CBD and few side effects. It should be important to know that we are not making any medical claims as these are not recognized in UK. 

As cannabis legalisation progresses and readily availablity of CBD Isolate, more doors will open, allowing more in-depth research into our ECS.

Chief Editor Casey A

This article is authored by Dr Casey Abrahamsmen. Dr Abrahamsmen is a board certified physician with over 13 years of experience in internal medicine and pain management. He practises Palliative care at a hospital in Venezuela and is a strong advocative for CBD and believes CBD has a major role to play towards healthy non addictive pain management habits. You can read more about Dr Abrahamsmen here.

This article was peer-reviewed by Dr M Mansoor Siddique (PhD). Dr Siddique has over eight years of experience working with CBD and CBD products.

Disclaimer: All of our products are not intended to diagnose, treat or cure any disease. It is recommended to check with doctor before starting a new dietary supplement program. All CBD products sold have less than 0.2% THC content and abide by both EU an UK law.



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